SUMMARY
Patients with endogenous depression fulfilling Feighner's criteria were included in the trial. All had pretrial scores above 20 on Hamilton's depression rating scale.
Drugs were divided into groups A and B. Group A comprised of placebo and d-amphetamine. It was found that all patients who improved with d-amphetamine also improved with tricyclics. Two who did not improve with d-amphetamine did not improve with tricyclics.
Full Text
The Full Text of this article is available as a PDF (117.4 KB).
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- LASAGNA L., VON FELSINGER J. M., BEECHER H. K. Drug-induced mood changes in man. I. Observations on healthy subjects, chronically ill patients, and postaddicts. J Am Med Assoc. 1955 Mar 19;157(12):1006–1020. doi: 10.1001/jama.1955.02950290026009. [DOI] [PubMed] [Google Scholar]
- Tecce J. J., Cole J. O. Amphetamine effects in man: paradoxical drowsiness and lowered electrical brain acitivity (CNV). Science. 1974 Aug 2;185(4149):451–453. doi: 10.1126/science.185.4149.451. [DOI] [PubMed] [Google Scholar]
- Van Kammen D. P., Murphy D. L. Attenuation of the euphoriant and activating effects of d- and l-amphetamine by lithium carbonate treatment. Psychopharmacologia. 1975 Nov 21;44(3):215–224. doi: 10.1007/BF00428897. [DOI] [PubMed] [Google Scholar]
- van Kammen D. P., Murphy D. L. Prediction of imipramine antidepressant response by a one-day dextro-amphetamine trial. Am J Psychiatry. 1978 Oct;135(10):1179–1184. doi: 10.1176/ajp.135.10.1179. [DOI] [PubMed] [Google Scholar]
