SUMMARY
Thyroid function viz. estimation of T3, T4 & TSH (Thyroid Stimulating Hormone) were studied in cases of depression, mania and schizophrenia, each category numbering thirty one. These values were compared with corresponding values estimated in norm.al control group of individuals of identical age, sex and socio economic status. The depressives and schizophrenics showed subclinical or chemical hypothyroidism while the manic showed slightly higher values for T3, and T4, when compared to normal control subjects.
Full Text
The Full Text of this article is available as a PDF (119.6 KB).
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- BERGER F. M. The pharmacological properties of 2-methyl-2-n-propyl-1,3-propanediol dicarbamate (miltown), a new interneuronal blocking agent. J Pharmacol Exp Ther. 1954 Dec;112(4):413–423. [PubMed] [Google Scholar]
- CADE J. F. A SIGNIFICANT ELEVATION OF PLASMA MAGNESIUM LEVELS IN SCHIZOPHRENIA AND DEPRESSIVE STATES. Med J Aust. 1964 Feb 8;1:195–196. doi: 10.5694/j.1326-5377.1964.tb114274.x. [DOI] [PubMed] [Google Scholar]
- Dewhurst K. E., El Kabir D. J., Harris G. W., Mandelbrote B. M. Observations on the blood concentration of thyrotrophic hormone (T.S.H.) in schizophrenia and the affective states. Br J Psychiatry. 1969 Sep;115(526):1003–1011. doi: 10.1192/bjp.115.526.1003. [DOI] [PubMed] [Google Scholar]
- KUHN R. The treatment of depressive states with G 22355 (imipramine hydrochloride). Am J Psychiatry. 1958 Nov;115(5):459–464. doi: 10.1176/ajp.115.5.459. [DOI] [PubMed] [Google Scholar]
- MacSweeney D., Timms P., Johnson A. Thryo-endocrine pathology, obstetric morbidity and schizophrenia: survey of a hundred families with a schizophrenic proband. Psychol Med. 1978 Feb;8(1):151–155. doi: 10.1017/s0033291700006735. [DOI] [PubMed] [Google Scholar]
- Prange A. J., Jr, Lara P. P., Wilson I. C., Alltop L. B., Breese G. R. Effects of thyrotropin-releasing hormone in depression. Lancet. 1972 Nov 11;2(7785):999–1002. doi: 10.1016/s0140-6736(72)92407-5. [DOI] [PubMed] [Google Scholar]
- Prange A. J., Jr, Wilson I. C., Rabon A. M., Lipton M. A. Enhancement of imipramine antidepressant activity by thyroid hormone. Am J Psychiatry. 1969 Oct;126(4):457–469. doi: 10.1176/ajp.126.4.457. [DOI] [PubMed] [Google Scholar]