SUMMARY
The present study includes 50 patients suffering from psychological stress disorders like thyrotoxicosis and anxiety neurosis. Biochemical estimation of melatonin was done in all these cases prior to treatment and 3 months after appropriate treatment. A significant increase in the level of melatonin was observed in thyrotoxic and anxiety neurotic cases. In all these cases, after therapy the level of melatonin was found to be within the normal limits. These observations confirm the finding that there is a pineal response to psychic stress.
Full Text
The Full Text of this article is available as a PDF (119.8 KB).
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Miline R., Krstić R., Devecerski V. Sur le comportement de la glande pinéale dans des conditions de stress. Acta Anat (Basel) 1968;71(3):352–402. [PubMed] [Google Scholar]
- Ozaki Y., Lynch H. J., Wurtman R. J. Melatonin in rat pineal, plasma, and urine: 24-hour rhythmicity and effect of chlorpromazine. Endocrinology. 1976 Jun;98(6):1418–1424. doi: 10.1210/endo-98-6-1418. [DOI] [PubMed] [Google Scholar]
- Wurtman R. J., Anton-Tay F. The mammalian pineal as a neuroendocrine transducer. Recent Prog Horm Res. 1969;25:493–522. doi: 10.1016/b978-0-12-571125-8.50014-4. [DOI] [PubMed] [Google Scholar]