Table 2.
KLK | Zn2+ | α1-AT | α1-ACT | ATIII | α2-AP | PCI | Kallistatin | Other serpins | LEKTI-1 | a2M** |
---|---|---|---|---|---|---|---|---|---|---|
KLK1 | ○ | ● [171] |
○ [196] |
○ [196] |
●● [308] |
●●● [196] |
●●● [229] |
|||
KLK2 | ● (3 μM)* [129] |
○ [172], [309] |
● [205], [172] |
●●● (+heparin) [187], [309] |
●●● [172], [309] |
●●● < 25 pM [129] |
●●● PI-6 [204] ●●● PAI-1 [205] |
●●● [230] [231] |
||
KLK3 | ● (24 μM) [134] |
●● [175], [176] |
●●● [232], [176] |
● [187] |
●● [192] |
●● MNEI [203] |
●●● [232] |
|||
KLK4 | ● (15 μM)* [137] |
●●● [178] |
○ [178] |
● [178] |
●● [178] |
● PAI-1 [155] |
● [178] |
|||
KLK5 | ● (4 μM) [15], [144] |
○/● [173], [170] |
○ [173] |
○ [173], [170] |
●●● [173], [170] |
●●● [170] |
○ [170] |
●● C1I [170] |
●● [218], [219] |
● [173] |
KLK6 | ○ | ● [174] |
● [182] |
●● [174] |
● [174] |
●● [63] |
○ [174] |
|||
KLK7 | ● (10 μM) [147] |
●●● [170] |
●●● [170] |
○ [170] |
●● [170] |
●●● [170] |
●●● [170] |
●● [218], [219] |
||
KLK8 | ● (3.3 μM) [123] |
○ [170] |
○ [170] |
● [170] |
●● [170] |
●●● [170] |
○ [170] |
●●● PI-6 [206] |
||
KLK11 | ○ [307] |
○ [307] |
○ [307] |
○ [307] |
● [170] |
○ [170] |
||||
KLK12 | ● (10 μM)* [17] |
●/●● [17], [170] |
○ [170] |
● [17], [170] |
●●● [17] |
●● [17] |
○ [170] |
●● C1I [17] |
○ [17] |
|
KLK13 | ○ [170] |
○ [170] |
● [170] |
●● [170] |
●●● [170] |
● [170] |
●● PAI-1 [170] |
●● [63] |
● [14] |
|
KLK14 | ● (2 μM) [15], [31] |
●● (162 nM) [63], [170] |
● (5.6 μm) [63] |
●● (198 nM) [63] |
●● (130 nM) [63], [170] |
●●● [170] |
●● [170] |
● PAI-1 [63] |
●● [63] |