Table 5.
Inflammatory mediator concentration in BAL fluid
| Mediator (pg/ml) | Respiratory virus (+) n=32 | Respiratory virus (−) n=32 | p value |
|---|---|---|---|
| IL-1 | 6.35 (3.09, 31.22) | 6.58 (1.24, 36.65) | 0.552 |
| IL-1a | 534.55 (292.43, 1753.36) | 524.84 (326.94, 1040.44) | 0.501 |
| IL-2 | not detected | not detected | |
| IL-4 | not detected | not detected | |
| IL-5 | not detected | not detected | |
| IL-6 | 22.79 (4.09, 194.46) | 32.46 (5.16, 310.08) | 0.981 |
| IL-7 | 1.61 1.19, 2.10) | 1.66 (1.36, 2.78) | 0.390 |
| IL-8 | 360.61 (161.00, 1592.96) | 204.85 (68.92, 1264.6) | 0.464 |
| IL-9 | 7.98 (2.68, 14.44) | 3.24 (0.63, 9.61) | 0.085 |
| IL-10 | 4.00 (2.49, 7.91) | 2.945 (1.33, 4.64) | 0.170 |
| IL-12 | 5.45 (3.31, 9.45) | 4.25 (2.04, 5.94) | 0.065 |
| IL-13 | 1.856 (1.24, 3.18) | 1.75 (0.975, 2.85) | 0.435 |
| IL-15 | 1.82 (0.07, 8.94) | 0.915 (0.2, 2.88) | 0.363 |
| IL-17 | 6.20 (0, 24.48) | not detected | |
| Basic FGF | not detected | not detected | |
| Eotaxin-1 | 6.98 (4.71, 25.94) | 5.39 (2.44, 11.78) | 0.017 |
| G-CSF | 23.55 (7.85, 97.77) | 14.26 (6.45, 76.03) | 0.421 |
| GM-CSF | not detected | not detected | |
| IFN-g | 12.21 (2.95, 34.84) | 9.81 (0.99, 19.57) | 0.144 |
| IP-10 | 8902.33 (2059.07, 57015.20) | 1246.82 (305.73, 4811.82) | <0.001 |
| CCL2/MCP-1 | 259.50 (61.71, 1583.27) | 240.03 (19.33, 578.28) | 0.296 |
| CCL3/MIP-1a | not detected | not detected | |
| CCL4/MIP-1b | 60.55 (29.16, 179.11) | 44.00 (27.72, 87.79) | 0.115 |
| PDGF-BB | 12.94 (6.38, 20.60) | 11.80 (4.81, 19.00) | 0.838 |
| CCL5/RANTES | 66.39 (25.41, 119.57) | 31.59 (11.23, 97.15) | 0.385 |
| TNF-a | 9.98 (0, 24.57) | 1.63 (0, 7.07) | 0.108 |
| VEGF | 36.42 (15.13, 80.55) | 35.37 (12.25, 70.86) | 0.995 |
Values were expressed as median (25%IQR, 75%IQR). “not detected” indicates level beneath the lower limit of detection of the assay. Definition of abbreviations: IQR=interquartile range.