Table 1.
WT (n = 17) |
NOS3-/- (n = 21) |
||
---|---|---|---|
Baseline | Heart Rate, bpm | 298 ± 50 | 265 ± 72 |
LVPmax, mmHg | 90.1 ± 12.8 | 111.3 ± 14.6a | |
dP/dtmax, mmHg/ms | 5.1 ± 0.83 | 5.9 ± 1.1a | |
τ, ms | 13.7 ± 1.5 | 14.9 ± 2.76 | |
Stroke Volume, μL | 11.9 ± 2.2 | 12.7 ± 3.8 | |
Ejection Fraction, % | 39.7 ± 14.4 | 39.6 ± 16.4 | |
PETCO2, mmHg | 39.7 ± 3.7 | 39.0 ± 3.2 | |
| |||
CPR Period | ROSC, n (%) | 14 (82.4) | 10 (47.6)b |
Time to ROSCc, s | 168 ± 58.8 | 140 ± 61.8 | |
CC rate, bpm | 311 ± 26.1 | 312 ± 27.4 | |
DBP, mmHg | 16.6 ± 7.3 | 18.0 ± 4.2 | |
PETCO2, mmHg | 26.8 ± 5.0 | 27.0 ± 4.8 |
p<0.05 compared to WT group (Mann-Whitney U test). Values displayed as mean ± standard deviation.
p<0.05 compared to WT group (Fisher’s exact test)Mann-Whitney U test).
ROSC animals only.