Transcription-dependent R-loop formation at mammalian class switch sequences. Tracey Robert B., Lieber Michael R. The EMBO Journal. 2000;19:1055–1067. doi: 10.1093/emboj/19.5.1055.
In the course of our carrying out experiments that were a direct extension of our recent EMBO J. paper on R-loop structures at class switch sequences (Tracey and Lieber, 2000), we discovered differences from those in the paper. The first author of that study (R.B.Tracey) has now admitted to making alterations in gel images that misrepresent the data. For this reason, the entire paper is being retracted. I am deeply regretful for any scientific misconceptions that may have resulted from this publication.
Michael Lieber
Please note that the following related paper is also being retracted for the same reason:
References
- Tracey R.B., Hsieh,C.-L. and Lieber,M.R. (2000) Stable RNA/DNA hybrids in the mammalian genome: inducible intermediates in immunoglobulin class switch recombination. Science, 288, 1058–1061. [DOI] [PubMed] [Google Scholar]