Table 1.
Host CNS genes induced by RV
| Gene/protein identification | GenBank accession no. | Method of identification | Function |
|---|---|---|---|
| IRF7 | U73037 | DD | Antiviral response |
| EBI-1 ligand chemokine | AF059208 | DD | Chemotactic factor for CD4 cells |
| Mouse MHC class I H2-D-b | M18523 | DD | Cytotoxic T-lymphocyte response |
| NADH-ubiquinone oxidoreductase | P03893 | DD | Respiratory chain protein |
| Genes encoding mitochondrial tRNA | MIMM01 | DD | The tRNAs for Phe, Val, and Leu |
| PSD-95 | D50621 | DD | Postsynaptic density protein |
| L26 | X80699 | DD | Ribosomal protein L26 |
| VL-30 retrotransposon (VL-30) | M21123 | DD | Virus-like retro-element |
| Replication-dependent histone H2A.1 | AA409282 | DD | DNA replication protein |
| Eyes absent homolog 2 | U71208 | cDNA array | Early eye development protein |
| Early growth response protein 3 | S40835 | cDNA array | Transcription factor |
| STAT-1 | U06924 | cDNA array | Transcription factor |
| Major prion protein precursor | M13685 | cDNA array | Scrapie-associated fibril protein |
| Programmed cell death 2 | U10903 | cDNA array | Cell death-associated protein |
| Trombomodulin | X14432 | cDNA array | Anticoagulant |
| VAMP1 | U61751 | cDNA array | Exo- and endocytosis |
| N-cadherin | M31131 | cDNA array | Cell adhesion |
| DNA-binding protein SMBP2 | L10075 | SH | DNA-binding protein |
| Semaphorin G | X97818 | SH | Axonal guidance |
| HSP-90 | S46109 | SH | Stress response |
| Glial cells missing gene homolog | U59876 | SH | Transcription factor |
| Insulin-like growth factor I receptor | U00182 | SH | Growth factor receptor |
| Sp4 zinc finger transcription factor | U62522 | SH | Transcription factor |
| Transcription termination factor 1 | X83974 | SH | DNA binding protein |
| Laminin receptor 1 | J02870 | SH | Receptor for laminin |
| Bcl-xL | L35049 | SH | Apoptosis-associated protein |
| GM-CSF receptor | M85078 | SH | Transmembrane receptor |
| Neuroleukin | M14220 | SH | Growth factor |
| Interleukin-5 receptor alpha subunit | D90205 | SH | Cytokine receptor |
| FHF-4 | P70379 | SH | Growth factor |
| Frizzled homolog 6 | U43319 | SH | Transmembrane receptor |
| Guanine nucleotide binding protein | Y00703 | SH | Signals transducer |
| Calmodulin | X61432 | SH | Calcium sensor protein |
| Apolipoprotein D (ApoD) | L39123 | RFDD | Ligand transporter |
| CDC10 | AJ223794 | RFDD | Postsynaptic density protein |
| Replacement histone H3.3 gene | X13605 | RFDD | DNA synthesis protein |
| GTP binding protein Gz | AF056972 | RFDD | Signal transduction |
| Metallothionein II | J03848 | RFDD | Metal inducible gene |
| L1 retrotransposon | M68842 | RFDD | Retro-element |