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Reducing SNF2H levels results in decreased ICP0 accumulation. (A) Immunoblot measuring the levels of HSV-1 immediate-early proteins in SNF2H-specific siRNA-transfected HEp2 cells relative to nontarget control siRNA-transfected cells. The cells were either mock infected or infected with HSV-1 at an MOI of 10 for the time indicated. (B) Quantification of the immunoblot in panel A, as described in Materials and Methods. a.u. arbitrary units.
