TABLE 1.
OUTCOME | REFERENCE(S) | OBSERVATIONS | COMMENT |
---|---|---|---|
Obesity | 16-20 | Increased fat mass | Fat accumulation is primarily subcutaneous fat |
Serum lipids | 18, 23 | Increased LDL cholesterol and triglycerides | HDL cholesterol is also increased |
Insulin sensitivity | 17, 24, 28 | Increased fasting plasma insulin and decreased insulin sensitivity | Small increase in glycosylated hemoglobin |
Blood pressure | 21 | No significant change | |
Waist-hip ratio | 21 | No significant change | |
C-reactive protein | 31 | No significant change in C-reactive protein or other biomarkers of inflammation |
LDL indicates low-density lipoprotein; HDL, high-density lipoprotein.