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. Author manuscript; available in PMC: 2011 Jan 21.
Published in final edited form as: Shock. 2009 Jun;31(6):621–626. doi: 10.1097/SHK.0b013e31818bbe21

Fig. 4. rFXIII reduces the severity of ileal mucosal damage after gut I/R injury.

Fig. 4

Hematoxylineosin staining. Original magnification ×100. A, Rat is subjected to SMAO and placebo treatment. Villi tips are disrupted. Red blood cell congestion is seen. Gut injury level is classified as grade 3 mucosal damage score. B, Rat is subjected to SMAO and rFXIII treatment. Extension of the subepithelial space as well as villi edema is seen. Gut injury level is classified as grade 2 mucosal damage score. C, Rat is subjected to sham SMAO and placebo treatment. Almost normal villi are seen (grade 0–1 mucosal damage score). D, Rat is subjected to sham SMAO and rFXIII treatment. Almost normal villi are seen (grade 0–1 mucosal damage score).