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. 1973 Oct;52(10):2451–2456. doi: 10.1172/JCI107436

Inhibition of Liver Fibrosis by L-Azetidine-2-Carboxylic Acid in Rats Treated with Carbon Tetrachloride

Marcos Rojkind 1
PMCID: PMC302504  PMID: 4729042

Abstract

L-Azetidine-2-carboxylic acid (AZC), an analogue of proline, has been shown to partially ameliorate hepatic cirrhosis induced in rats by CCl4. AZC caused a diminution in formation of collagen in the liver accompanied by a relative decrease in the pool of free proline. The synthesis of noncollagenous proteins in the livers of treated rats did not appear to be affected.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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