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. 2010 Nov 15;32(2):233–239. doi: 10.1093/carcin/bgq235

Table I.

Survival rates of mice in the study

Genotype Treatment Duration (weeks) No. of mice treated Surviving mice
1 week after PhIP or DMSO (%) 1 week after DSS (%)
hCYP1A 200 mg/kg PhIP + 1.5% DSS 6–10 58 52 (90) 49 (84)
hCYP1A DMSO + 1.5% DSS 6–10 20 20 (100) 18 (90)
hCYP1A DMSO 24 17 17 (100) 17 (100)
hCYP1A 200 mg/kg PhIP 16–24 30 28 (93) 28 (93)
Wild-type 200 mg/kg PhIP + 1.5% DSS 24 11 11 (100) 11 (100)
Wild-type DMSO 24 17 17 (100) 17 (100)
Wild-type 200 mg/kg PhIP 14–24 17 17 (100) 17 (100)

Mice were given 200 mg/kg PhIP or vehicle (DMSO) by oral gavage and 1 week later were given 0 or 1.5% DSS in the drinking water for 7 days. Duration indicates the number of weeks following PhIP or DMSO administration when the mice were sacrificed.