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Immunohistochemistry showing the ontogeny of GIP ligand (A, C, and E) and GIPR (B, D, and F). GIP ligand is present in the early embryonic pancreas, and the expression increases during late gestational ages. GIPR expression was weak at early ages, but strong expression was found at later gestational ages (magnification size bars: A and B = 20 μmol/L; C and D = 50 μmol/L; E and F = 100 μmol/L).
