. 2010 Jul 27;12(1):41–50. doi: 10.1007/s10048-010-0253-6

Table 6.

Association studies of detected single nucleotide polymorphism (SNPs) with the clinical phenotypes of Japanese adrenoleukodystrophy patients: known SNPs

Gene	SNP ID	Allele frequency (number)			p value^b
Gene	SNP ID	Cerebral form (a total of 44 chromosomes)	AMN (a total of 26 chromosomes)	Control (number of detected SNPs/total number)	Cerebral form vs AMN	Cerebral form vs control	AMN vs control
ABCD3	Rs4148058	11	5	22/164	0.7697	0.1010	0.3820
	Rs2147794	6	2	34/152	0.7009	0.2880	0.0740
	Rs16946	6	3	35/164	1.0000	0.2933	0.3019
	Rs681187	17	9	75/158	1.0000	0.3109	0.2890
	Rs662813	18	10	42/152	1.0000	0.0984	0.1435
	Rs337592	2	4	19/152	0.1855	0.1714	0.7512
ABCD4	Rs17782508^a	9	2	42/164	0.1921	0.5575	0.0468
	Rs17182959	10	7	40/128	0.5599	0.3386	0.8163
	Rs17158118	10	7	33/162	0.5599	0.8344	0.4454
	Rs2301345^a	9	2	42/164	0.1921	0.5575	0.0468
	Rs4148077^a	9	2	42/164	0.1921	0.5575	0.0468
	Rs4148078^a	9	2	42/164	0.1921	0.5575	0.0468
	Rs3742801^a	9	2	42/164	0.1921	0.5575	0.0468

^aFive SNPs (rs17782508, rs2301345, rs4148077, rs4848078, and rs3742801) were in complete disequilibrium in the Japanese population

^bResults of two-sided Fisher's exact test