Skip to main content
NCBI home page
Infection and Immunity logoLink to Infection and Immunity
. 1994 Aug;62(8):3580–3582. doi: 10.1128/iai.62.8.3580-3582.1994

Experimental Borrelia garinii infection of Japanese quail.

E Isogai 1, S Tanaka 1, I S Braga 3rd 1, C Itakura 1, H Isogai 1, K Kimura 1, N Fujii 1
PMCID: PMC302998  PMID: 8039933

Abstract

Japanese quail inoculated subcutaneously with Borrelia garinii responded to infection. B. garinii was reisolated mainly from skin and randomly from several organs between 7 and 56 days postinoculation. Skin lesions were occasionally observed in association with spirochete recovery. All birds were positive for antibody at 53 to 56 days postinoculation. These results suggest that the Japanese quail is a model for experimental infection with B. garinii and that birds are reservoirs for Lyme disease spirochetes.

Full text

PDF
3580

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Anderson J. F., Johnson R. C., Magnarelli L. A., Hyde F. W. Involvement of birds in the epidemiology of the Lyme disease agent Borrelia burgdorferi. Infect Immun. 1986 Feb;51(2):394–396. doi: 10.1128/iai.51.2.394-396.1986. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Anderson J. F., Magnarelli L. A. Avian and mammalian hosts for spirochete-infected ticks and insects in a Lyme disease focus in Connecticut. Yale J Biol Med. 1984 Jul-Aug;57(4):627–641. [PMC free article] [PubMed] [Google Scholar]
  3. Anderson J. F., Magnarelli L. A. Vertebrate host relationships and distribution of ixodid ticks (Acari: Ixodidae) in Connecticut, USA. J Med Entomol. 1980 Jul 31;17(4):314–323. doi: 10.1093/jmedent/17.4.314. [DOI] [PubMed] [Google Scholar]
  4. Baranton G., Postic D., Saint Girons I., Boerlin P., Piffaretti J. C., Assous M., Grimont P. A. Delineation of Borrelia burgdorferi sensu stricto, Borrelia garinii sp. nov., and group VS461 associated with Lyme borreliosis. Int J Syst Bacteriol. 1992 Jul;42(3):378–383. doi: 10.1099/00207713-42-3-378. [DOI] [PubMed] [Google Scholar]
  5. Barbour A. G. Isolation and cultivation of Lyme disease spirochetes. Yale J Biol Med. 1984 Jul-Aug;57(4):521–525. [PMC free article] [PubMed] [Google Scholar]
  6. Burgess E. C. Experimental inoculation of mallard ducks (Anas platyrhynchos platyrhynchos) with Borrelia burgdorferi. J Wildl Dis. 1989 Jan;25(1):99–102. doi: 10.7589/0090-3558-25.1.99. [DOI] [PubMed] [Google Scholar]
  7. Donahue J. G., Piesman J., Spielman A. Reservoir competence of white-footed mice for Lyme disease spirochetes. Am J Trop Med Hyg. 1987 Jan;36(1):92–96. doi: 10.4269/ajtmh.1987.36.92. [DOI] [PubMed] [Google Scholar]
  8. Fukunaga M., Sohnaka M., Takahashi Y., Nakao M., Miyamoto K. Antigenic and genetic characterization of Borrelia species isolated from Ixodes persulcatus in Hokkaido, Japan. J Clin Microbiol. 1993 May;31(5):1388–1391. doi: 10.1128/jcm.31.5.1388-1391.1993. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Fukunaga M., Sohnaka M., Yanagihara Y. Analysis of Borrelia species associated with Lyme disease by rRNA gene restriction fragment length polymorphism. J Gen Microbiol. 1993 Jun;139(Pt 6):1141–1146. doi: 10.1099/00221287-139-6-1141. [DOI] [PubMed] [Google Scholar]
  10. Isogai E., Isogai H., Sato N., Yuzawa M., Kawakami M. Antibodies to Borrelia burgdorferi in dogs in Hokkaido. Microbiol Immunol. 1990;34(12):1005–1012. doi: 10.1111/j.1348-0421.1990.tb01522.x. [DOI] [PubMed] [Google Scholar]
  11. McLean R. G., Ubico S. R., Hughes C. A., Engstrom S. M., Johnson R. C. Isolation and characterization of Borrelia burgdorferi from blood of a bird captured in the Saint Croix River Valley. J Clin Microbiol. 1993 Aug;31(8):2038–2043. doi: 10.1128/jcm.31.8.2038-2043.1993. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Picken R. N. Polymerase chain reaction primers and probes derived from flagellin gene sequences for specific detection of the agents of Lyme disease and North American relapsing fever. J Clin Microbiol. 1992 Jan;30(1):99–114. doi: 10.1128/jcm.30.1.99-114.1992. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Russell H., Sampson J. S., Schmid G. P., Wilkinson H. W., Plikaytis B. Enzyme-linked immunosorbent assay and indirect immunofluorescence assay for Lyme disease. J Infect Dis. 1984 Mar;149(3):465–470. doi: 10.1093/infdis/149.3.465. [DOI] [PubMed] [Google Scholar]
  14. Weisbrod A. R., Johnson R. C. Lyme disease and migrating birds in the Saint Croix River Valley. Appl Environ Microbiol. 1989 Aug;55(8):1921–1924. doi: 10.1128/aem.55.8.1921-1924.1989. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Wilske B., Barbour A. G., Bergström S., Burman N., Restrepo B. I., Rosa P. A., Schwan T., Soutschek E., Wallich R. Antigenic variation and strain heterogeneity in Borrelia spp. Res Microbiol. 1992 Jul-Aug;143(6):583–596. doi: 10.1016/0923-2508(92)90116-6. [DOI] [PubMed] [Google Scholar]

Articles from Infection and Immunity are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES