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. 1994 Sep;62(9):4066–4071. doi: 10.1128/iai.62.9.4066-4071.1994

Experimental infection of young chicks with attaching and effacing Escherichia coli.

M Sueyoshi 1, M Nakazawa 1
PMCID: PMC303070  PMID: 8063426

Abstract

Young chicks were inoculated with six different strains of attaching and effacing Escherichia coli isolated from the feces of calves, pigs, chicks, and humans. Colibacilli of some serotypes had colonized the cecum of chicks by 7 days after inoculation. The characteristic lesions associated with bacterial attachment were also seen on the mucosal surface of the cecum. Electron microscopy revealed numerous colibacilli closely attached to the surface membrane of enterocytes. Cell membranes formed cups and pedestals at the base of the attached bacilli. The results of this study support the conclusion that young chicks can be used as a model for the study of the lesions caused by attaching and effacing E. coli strains.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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