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. 1994 Sep;62(9):4072–4074. doi: 10.1128/iai.62.9.4072-4074.1994

Humoral immune response to the Trypanosoma cruzi complement regulatory protein as an indicator of parasitologic clearance in human Chagas' disease.

K A Norris 1, L M Galvão 1, J E Schrimpf 1, J R Cançado 1, A U Krettli 1
PMCID: PMC303071  PMID: 8063427

Abstract

Immunoprecipitation of the purified 160-kDa complement regulatory protein of Trypanosoma cruzi by Chagas' disease patient sera was examined as a possible correlate of the complement-mediated lysis test and as an indicator of parasite clearance. The results presented demonstrate that assessment of the humoral response to this antigen is a useful indicator of parasite clearance and may be particularly helpful in the assessment of some patients for whom other serological tests produce ambiguous results.

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Selected References

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