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. 2010 Sep 10;116(25):e139–e149. doi: 10.1182/blood-2010-05-283879

Table 3.

Multiple regression models for each cross

Chr@Mb df LOD % Variance* F P
Cross 129S1xA
    Sex 1 12.03 12.7 58.51 3.24 × 10−13
    8@120.5 6 6.88 7.0 5.34 3.08 × 10−5
    14@67.6 6 5.71 5.7 4.39 2.91 × 10−4
    9@102.3 2 14.53 15.7 36.06 1.15 × 10−14
    8@120.5:14@67.6 4 5.53 5.5 6.37 6.37 × 10−5
    Total 38.9
Cross AxB
    Sex 1 4.48 4.2 20.88 6.42 × 10−6
    7@114.5 2 6.75 6.3 15.90 2.19 × 10−7
    9@107.5 2 4.03 3.7 9.34 1.07 × 10−4
    Total 14.4
Cross BxD
    Sex 1 5.36 5.1 25.16 7.71 × 10−7
    7@94.4 2 7.37 7.1 17.48 4.99 × 10−8
    Total 11.7
Cross BxCB
    7@121.8 2 4.45 17.7 11.00 4.73 × 10−5
Cross Bx129S1
    Sex 1 16.37 6.5 80.22 < 2.0 × 10−16
    2@109.6 2 5.38 2.0 12.49 5.16 × 10−6
    6@94.9 2 3.45 1.3 7.95 4.1 × 10−4
    7@110.0 2 83.57 47.2 289.39 < 2.0 × 10−16
    Total 61.3
Cross CByx129S1
    Sex 3 11.11 10.3 17.76 6.97 × 10−11
    9@59.3 4 4.86 4.4 5.63 2.0 × 10−4
    9@104.0 2 6.31 5.7 14.75 6.40 × 10−7
    9@59.3:sex 2 4.46 4.0 10.32 4.19 × 10−5
    Total 16.9
Cross CByxC3
    Sex 1 11.00 10.7 53.23 1.43 × 10−12
    6@59.4 2 3.61 3.36 8.40 2.64 × 10−4
    Total 13.3
Cross C3xD
    Sex 3 6.58 6.3 10.21 1.65 × 10−6
    1@81.7 2 2.58 2.4 5.89 .01
    2@113.5 2 2.32 2.2 5.29 .01
    12@77.7 4 3.33 3.1 3.82 .01
    12@77.7:sex 2 2.53 2.4 5.76 .01
    Total 12.1
Cross MRxSM
    Sex 3 2.80 2.6 4.26 .01
    2@33.0 2 3.07 2.8 7.00 .01
    7@110.6 2 21.11 21.6 54.19 < 2.0 × 10−16
    8@16.9 4 4.23 3.9 4.86 .001
    8@16.9:sex 2 2.67 2.4 6.08 .01
    Total 29.5
Cross KSxSM
    Sex 3 8.75 12.8 13.86 3.88 × 10−8
    2@77.5 2 3.97 5.5 8.87 2.15 × 10−4
    6@116.5 2 2.72 3.7 5.99 .01
    9@69.6 4 4.99 7.0 5.65 .001
    9@107.6 2 3.77 5.2 8.42 .001
    18@68.3 2 2.81 3.8 6.19 .01
    9@69.6:sex 2 2.67 3.6 5.88 .01
    Total 47.1
Cross NZxSM
    Sex 1 7.97 11.8 39.33 2.68 × 10−9
    7@105.6 2 19.37 33.4 55.64 < 2.0 × 10−16
    11@80.2 2 4.15 5.9 9.74 9.72 × 10−5
    Total 47.2
Cross BxWSB
    7@112.1 1 18.8 33.7 106.06 < 2.0 × 10−16

df indicates degrees of freedom (includes main effect QTL and interactions).

*

Variance is the percentage of the total phenotypic variance in the F2 population associated with each location.