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. 1994 Nov;62(11):5151–5153. doi: 10.1128/iai.62.11.5151-5153.1994

Endothelial cell proliferation associated with lesions of murine systemic candidiasis.

R B Ashman 1, J M Papadimitriou 1
PMCID: PMC303237  PMID: 7523305

Abstract

Neovascularization is associated with tumor growth and some inflammatory diseases but has not been reported to be induced by infectious agents. In a mouse model of systemic Candida albicans infection, extensive endothelial cell proliferation was seen in the periphery of brain abscesses and in the areas of fungal pyelonephritis in the kidney. This finding is important for an understanding of the pathogenesis of fungal infections and may contribute to an analysis of the mechanisms of angiogenesis.

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Selected References

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