Skip to main content
. 2010 Sep 21;117(1):283–289. doi: 10.1182/blood-2010-07-299057

Table 1.

TEG-derived values for global whole blood coagulation parameters of transgenic mouse lines

R (minutes) K (minutes) A (°) MA (mm) n
WT
    0 7.3 ± 2.1 3.3 ± 1.2 52.4 ± 3.4 64.5 ± 2.1 9
    12 hours 19.8 ± 3.5* 11.7 ± 2.5* 18.6 ± 3.7* 30.8 ± 4.1* 6
PC−/−PC(tg4)/TF−/−hTF(tg)
    0 21.3 ± 1.9* 8.9 ± 1.2* 25.3 ± 2.2* 56.3 ± 3.0* 6
    12 hours > 120 0 0 0 6
PC−/−PC(tg785) 13.0 ± 3.2* 4.8 ± 2.0 48.3 ± 4.7 65.0 ± 3.2 8
TF−/−hTF(tg) 19.9 ± 2.1* 7.4 ± 1.1* 31.5 ± 3.2* 63.8 ± 4.6 7
Fg−/− > 120 0 0 0 6
Fg+/− 4.7 ± 0.9 1.8 ± 0.3 64.4 ± 3.3* 61.3 ± 1.5 5
*

P < .05 from WT mice.

P < .05 from all mice tested, except when compared with Fg−/−.

P < .05 from all mice tested, except when compared with PC−/−(tg4)/hTF−/−(tg) at 12 hours post-LPS.