Fig. 7. Combined treatment with HS and MRS-1191 improves survival after sepsis.
Mice subjected to CLP were treated with HS (4 ml/kg) with or without MRS-1191 (2 ng/kg), either 10 min before or 60 min after CLP and survival was monitored. At the 24-h time point, survival rates in the HS pretreatment group and the delayed HS treatment group with MRS-1191 differed significantly from all other group (Kaplan-Meier, n=11, *p<0.05).