Percent increases of diameter and flow after 1st, 5th, and 15th min of applied local heat. Percent increases in both flow and diameter during min 1, 5, and 15 were significantly elevated from baseline (p<0.05). A) Only 5th order vessels displayed a trend (p=0.08) toward a biphasic vasodilatory response with min 1 and 15 being significantly higher than min 5. B) With the exception of the 4th order, all vessel orders displayed a trend toward a biphasic flow response (BFR) to local heat, though not statistically detectable by repeated-measures ANOVA.