Table 3.

Chromosal linkages for F-T4 in recombinant inbred mice (AXBXA, BXD, BXH, and CXB strains)

Chr	Strain	LRS	LOD	Mb	Hu Chr	Gene/assoc
2	AXBXA	20.301	4.41	106.692	11p13	(FSHb)
1	BXD	10.762	2.34	117.558 to	2q14.2	(Ptpn4)
				125.82	2q14.1
				157.504	1q25.2
				164.317	1q23
				164.587	1q24.3	a
				171.142 to	1q23.3
	BXH	14.729	3.20	179.106	1q43-q44	(Akt3)
				117.066	10q11.2	(Ret)
				119.083	12p13.33
6	BXD	14.735	3.20	119.377	12p13.31
				103.772	5q14.3	Pde8bb
13	CXB	15.37	3.34	104.23	5q12
				69.158	18q21.2	(Rab27b)
				77.031	18q21.1	Ref.c
18	BXH	14.73	3.20	77.841	18q21.1
				23.654	9q21.12
19	CXB	15.37	3.34	25.403	9p24.3

As in Table 1, data are presented for suggestive LRS values or LOD scores (LOD = LRS/4.6). Also included are locations of loci (megabases, Mb), corresponding human Chr, and the closest genes or previously observed associations.

Chr 1: Akt3, thymoma viral proto-oncogene 3 (178.952245 Mb); Ptpn4, protein tyrosine phosphatase nonreceptor type 4 (121.554669 Mb). Chr 2: FSHb, follicle stimulating hormone &β (106.8963 Mb). Chr 6: Ret, ret proto-oncogene (118.101765 Mb). Chr 13: Pde8b and Pde4d, phosphodiesterase 8B and 4D (95.79446 Mb, 109.77500 Mb). Chr 18: Rab27b: RAS oncogene family (70.13878 Mb).

^aAs for BXD T-T4, Chr 1 (Table 1).

^bTSH in humans (26).

^cF-T4 in humans (25).