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. Author manuscript; available in PMC: 2012 Mar 1.
Published in final edited form as: Pain. 2010 Dec 13;152(3 Suppl):S49–S64. doi: 10.1016/j.pain.2010.11.010

Figure 13.

Figure 13

Whole-brain relationship between grey and white matter is disrupted in chronic complex regional pain syndrome subjects. Left panel shows that white matter fractional anisotropy (FA; measured for group average skeleton which insures that the tissue examined has 95% probability of being white matter) is correlated to total neocortical volume of the brain (after correcting for age effects). The right panel is similar data in complex regional pain syndrome patients, and shows that the relationship is destroyed. In both panels each symbol is the brain of a subject, red = healthy controls, blue = patients. Adapted from [41].