TABLE 3.
Cost per influenza case avoided through vaccination with the H1N1 vaccine for the commercially insured and uninsureda
| Commercial Insurance | Uninsured | ||||
|---|---|---|---|---|---|
| Time for Vaccination (hrs) | Attack Rate | Attack Rate | |||
| Baseline Scenariob, c | Sensitivity Analyses 6.5%d | Baseline Scenariob, c | Sensitivity Analyses 6.5%d | ||
| Vaccine Cost = $0 | |||||
| 1 hr | LAIV | 16 (−187–275) | 202 (−61–548) | 14 (−206–263) | 204 (−115–576) |
| TIV | 27 (−180–295) | 225 (−48–575) | 29 (−228–273) | 238 (−79–624) | |
| 2 hrs | LAIV | 240 (−56–690) | 604 (164–1,170) | 231 (−90–729) | 601 (143–1,256) |
| TIV | 256 (−50–728) | 664 (196–1,294) | 256 (−73–762) | 657 (158–1,319) | |
| 4 hrs | LAIV | 675 (169–1,573) | 1,407 (582–2,591) | 665 (137–1,528) | 1,391 (556–2,647) |
| TIV | 720 (158–1,648) | 1,487 (574–2,734) | 723 (155–1,638) | 1,502 (605–2,920) | |
| Vaccine Cost = $15 | |||||
| 1 hr | TIV | 193 (−54–508) | 527 (196–919) | 723 (155–1,638) | 528 (168–943) |
| 2 hrs | TIV | 426 (54–986) | 969 (451–1,678) | 427 (64–983) | 957 (413–1,682) |
| 4 hrs | TIV | 868 (307–1,837) | 1,791 (837–3,182) | 865 (250–1,734) | 1,792 (831–3,185) |
| Vaccine Cost = $25 | |||||
| 1 hr | LAIV | 270 (22–654) | 675 (365–1,077) | 277 (5–650) | 675 (318–1,100) |
| 2 hrs | LAIV | 492 (133–1,021) | 1,089 (588–1,750) | 484 (115–1,009) | 1,069 (549–1,780) |
| 4 hrs | LAIV | 904 (320–1,822) | 1,896 (1,016–3,202) | 911 (334–1,793) | 1,860 (966–3,164) |
| Vaccine Cost = $50 | |||||
| 1 hr | LAIV | 523 (212–989) | 1,140 (144–1,652) | 519 (195–978) | 1,155 (713–1,704) |
| TIV | 584 (208–1,110) | 1,222 (790–1,783) | 573 (223–1,127) | 1,244 (777–1,824) | |
| 2 hrs | LAIV | 746 (317–1,382) | 1,535 (961–2,288) | 742 (316–1,434) | 1,571 (1,000–2,360) |
| TIV | 824 (365–1,534) | 1,663 (1,051–2,558) | 821 (358–1,550) | 1,675 (1,038–2,534) | |
| 4 hrs | LAIV | 1,141 (519–2,128) | 2,342 (1,382–3,724) | 1,162 (515–2,257) | 2,377 (1,339–3,874) |
| TIV | 1,274 (527–2,488) | 2,591 (1,526–3,908) | 1,268 (572–2,440) | 2,534 (1,441–4,014) | |
| Vaccine Cost = $150 | |||||
| 1 hr | LAIV | 1,543 (874–2,590) | 3,027 (2,256–4,091) | 1,563 (882–2,605) | 3,046 (2,249–4,182) |
| TIV | 1,645 (953–2,786) | 3,217 (2,406–4,320) | 1,657 (937–2,823) | 3,265 (2,374–4,384) | |
| 2 hrs | LAIV | 1,769 (986–2,995) | 3,430 (2,460–4,668) | 1,750 (1,013–2,897) | 3,425 (2,479–4,820) |
| TIV | 1,837 (1,067–3,165) | 3,688 (2,683–5,250) | 1,870 (1,094–3,281) | 3,683 (2,628–5,090) | |
| 4 hrs | LAIV | 2,187 (1,221–3,901) | 4,201 (2,959–5,927) | 2,217 (1,182–3,921) | 4,188 (2,903–5,968) |
| TIV | 2,356 (1,302–4,174) | 4,533 (3,109–6,322) | 2,387 (1,305–4,201) | 4,481 (3,049–6,368) | |
a
median (95% confidence interval)
b
Triangular distribution: Min = 6.5%, Likeliest = 11.5%, Max = 19.4
c
Most likely attack rate
d
Based on a distribution generated from data collected by Miller et al, the probability of a 6.5% attack rate of seasonal influenza is approximately <1