TABLE 1.
Metabolic data at 8 weeks after inducing diabetes
| Control | DM | DM+GW0742 | |
|---|---|---|---|
| n | 6 | 7 | 7 |
| Systolic blood pressure (mmHg) | 97.8 ± 7.9 | 111.8 ± 4.4 | 110.1 ± 3.5 |
| HbA1c (%) | 4.60 ± 0.04 | 9.75 ± 0.34* | 8.81 ± 0.62* |
| Body weight (g) | 26.75 ± 0.39 | 17.74 ± 1.03* | 20.70 ± 0.41*† |
| Kidney weight (mg) | 283.3 ± 3.3 | 325.7 ± 18.8‡ | 295.7 ± 6.1 |
| Relative kidney weight (mg/g body wt) | 11.82 ± 0.27 | 18.85 ± 1.87* | 15.87 ± 0.57 |
| Creatinine clearance (mL/min) | 249.0 ± 34.8 | 349.5 ± 40.4 | 348.1 ± 44.7 |
| Triglycerides (mg/dL) | 23.6 ± 2.0 | 27.9 ± 7.3 | 21.5 ± 4.8 |
Data are means ± SE.
*P < 0.01 vs. the control group.
†P < 0.01 vs. the DM group.
‡P < 0.05 vs. the control group.