Page 5063. The first sentence of the second paragraph in the left column should be replaced by the following: “In an impressively comprehensive study on several series of thrombin inhibitors, the Hangauer and Klebe groups have analyzed the sources of cooperativity between a lipophilic interaction and a hydrogen bond”.30,31
Page 5075. Figure 16 caption should read as follows: “Radial distribution of carbon atoms around phenyl rings: (a) CH3 bound to O or N (CSD statistics); (b) CH3 bound to sp3 C (CSD statistics); (c) CH3 bound to O or N (PDB statistics). Darker gray corresponds to higher density; peaks above a numerical value of 90 are colored red”.
Page 5083. Reference 159 should be replaced by the following: Manley P. W.; Cowan-Jacob S. W.; Fendrich G.; Mestan J.. Molecular interactions between the highly selective pan-Bcr-Abl inhibitor, AMN107, and the tyrosine kinase domain of Abl. Blood 2005, 53, 940a−941a.
Funding Statement
National Institutes of Health, United States