Skip to main content
The Journal of Biological Chemistry logoLink to The Journal of Biological Chemistry
. 2011 Mar 11;286(10):8707. doi: 10.1074/jbc.A110.807952

Structure of the capsular polysaccharide of pneumococcal serotype 11A reveals a novel acetylglycerol that is the structural basis for 11A subtypes.

Edward R Zartler, Richard J Porambo, Carrie L Anderson, Lorenzo H Chen, Jigui Yu, Moon H Nahm
PMCID: PMC3048752

VOLUME 284 (2009) PAGES 7318–7329

In subsequent work following up on this initial study, we discovered a typographical error in the assignments of the core polysaccharide structure. The error was a transposition of the assignments for α1 (αGal) and α2 (αGlc) H-6/H-6′. This led to the conclusion that the polysaccharide was branched. This is in error, and the original proposed core structure is correct (i.e. linear subunit). This error affects Figs. 4, 7, and 9 in this article. However, this error does not impact the main finding of our paper: the discovery of different acetylation patterns for the two clinical isolates (ST11Aα and ST11Aβ) of ST11A. (ST11Aβ is now referred to as ST11E (Calix, J. J., and Nahm, M. H. (2009) J. Infect. Dis. 202, 29–38).) The revised structures for ST11A and ST11E are shown below. We apologize for any inconvenience this may have caused.

graphic file with name zbc0101156150001.jpg


Articles from The Journal of Biological Chemistry are provided here courtesy of American Society for Biochemistry and Molecular Biology

RESOURCES