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Localisation of COX-2 immunostaining in the sebaceous gland of acne patients (A) and in the normal skin of healthy controls (B). Very strong immunoreaction of the gene within the sebaceous gland of acne skin, especially, in undifferentiated and early differentiated sebocytes is seen (A) (x400). Weak immunoexpression of COX-2 in the sebaceous gland and ductal cells of healthy skin (B) (x400).
