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Journal of Korean Medical Science logoLink to Journal of Korean Medical Science
. 1992 Sep;7(3):264–270. doi: 10.3346/jkms.1992.7.3.264

'Pauci-immune' rapidly progressive glomerulonephritis associated with systemic vasculitis.

J Y Han 1, S A Yoon 1, J Y Woo 1, I S Park 1, S Y Kim 1, Y S Chang 1, B K Bang 1
PMCID: PMC3053772  PMID: 1285926

Abstract

'Pauci-immune' glomerulonephritis has been recognized as an important cause of rapidly progressive glomerulonephritis. The paucity of immune deposits can be separated from the other two major immunohistologic variants of crescentic glomerulonephritis, ie, antiglomerular basement membrane (GBM) antibody-mediated and immune complex-mediated glomerulonephritis. Here we describe the case of a 42-year-old woman with pauci-immune' glomerulonephritis and vasculitis presenting as rapidly progressive renal failure with characteristic pathologic and immunohistologic findings. And in this case, despite oliguria and rapid deterioration of renal function, the renal function recovered partially and continued to be stabilized with a favourable response to hemodialysis and combined system immunosuppressive therapy.

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