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Journal of Korean Medical Science logoLink to Journal of Korean Medical Science
. 2002 Feb;17(1):113–115. doi: 10.3346/jkms.2002.17.1.113

Penicillin-resistant Aerococcus viridans bacteremia associated with granulocytopenia.

Young Uh 1, Jeong Seog Son 1, In Ho Jang 1, Kap Jun Yoon 1, Soon Ki Hong 1
PMCID: PMC3054839  PMID: 11850599

Abstract

Aerococcus viridans, a catalase-negative gram-positive coccus rarely causing bacteremia, was isolated from blood cultures of a 52-yr-old man under the granulocytopenic condition. The isolate showed the typical characteristics of A. viridans, i.e., tetrad arrangements in gram stain, positive pyrrolidonyl aminopeptidase (PYR) and negative leucine aminopeptidase (LAP) reactions, and no growth at 45 degrees C. The isolate was revealed to be highly resistant to penicillin, erythromycin, clindamycin, and ceftriaxone, although most strains of A. viridans isolated from the previously reported patients were susceptible to penicillin and other commonly used antibiotics. Even though A. viridans is rarely associated with human infections, it could be a potential causative agent of bacteremia, especially in immunocompromised patients.

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