Figure 2.
Effect of L-arginine administration and arginase inhibition on vasomotor function. Coronary arteriolar dilation to serotonin (Control; n=14) was inhibited by OxLDL (0.5 mg protein/ml; n=5). Administration of L-arginine (L-Arg, 3 mM; n=4) or arginase inhibitor DFMO (0.4 mM; n=5) restored vasodilation to serotonin. *P<0.05 vs. Control.