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. 1987 Jul 10;15(13):5199–5215. doi: 10.1093/nar/15.13.5199

Transcription of a human transposon-like sequence is usually directed by other promoters.

K E Paulson, A G Matera, N Deka, C W Schmid
PMCID: PMC305956  PMID: 3037490

Abstract

The transcriptional activity of a human transposon-like family of repeats, called the THE-1 family, has been studied in cell culture and in human tissue. Both strands of THE-1 are present in several discrete length poly A plus RNAs. Primer extension studies and the structures of cDNA clones show that these THE-1 transcripts are usually the product of other transcription units. The THE-1 LTR provides the polyadenylation processing site for two transcripts, which result from upstream non THE-1 promoters. Yet another transcript, containing an internal THE-1 element in the probable sense orientation, is greatly enriched in a polysomal size fraction.

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