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. Author manuscript; available in PMC: 2011 Mar 21.
Published in final edited form as: Cancer. 2009 Sep 1;115(17):3897–3908. doi: 10.1002/cncr.24445

Figure 2. MEKK3 is overexpressed in ovarian carcinomas and parallels with increased IKK kinase activity and constitutive NFκB activity.

Figure 2

(A) Whole-cell extracts from ovarian carcinomas were used for western blotting with anti-MEKK3, anti-IKKβ, and β-actin. A portion of the same tumor samples were used to prepare detergent-soluble extracts for IKK kinase assays. (B) Nuclear and whole-cell extracts from ovarian carcinomas were used for, respectively, EMSA and western blot with anti-p65 antibodies.