Abstract
Background
High blood pressure is the single most important risk factor worldwide for the development of cardiovascular disease, and has been shown to affect some ethnic minority groups disproportionately.
Aim
To explore ethnic inequalities in blood pressure monitoring and control.
Method
Data from Lambeth DataNet was used, based on case records from GP practices in one inner-city London borough. Blood pressure monitoring and control was compared using Quality and Outcomes Framework (QOF) targets for patients with: diabetes, coronary heart disease, stroke, hypertension, and chronic kidney disease. The study controlled for age, sex, social deprivation, and clustering within GP practices.
Results
A total of 16 613 patients met the study criteria, with 5962 categorised as black/black British. Blood pressure monitoring was similar across ethnic groups and as good, if not better, for black patients compared to white. However, marked ethnic inequalities in blood pressure control were found, with black patients significantly less likely to achieve QOF targets than their white counterparts (odds ratio [OR] 0.73; 95% confidence interval [CI] = 0.64 to 0.82). Further inequalities were revealed in blood pressure control within disease groups and ethnic subgroups. In particular, blood pressure control was poor in African patients with diabetes (OR 0.63; 95% CI = 0.50 to 0.79) and Caribbean patients with coronary heart disease (OR 0.53; 95% CI = 0.37 to 0.77) when compared with white patients.
Discussion
While black patients with chronic conditions are equally likely to have their blood pressure monitored, their blood pressure control is consistently poorer than that of their white counterparts. This may have important implications for cardiovascular risk management in black patients.
Keywords: ethnicity/race, inequalities, health care, hypertension
INTRODUCTION
The burden of cardiovascular disease is unevenly distributed within the general population. For example, the incidence of coronary heart disease (CHD) has been shown to be consistently higher among South Asians, while the incidence of stroke is more common among African–Caribbean individuals compared to the white population.1,2 Furthermore, socioeconomically deprived populations experience higher rates of both heart disease and stroke.3,4
Differences in the incidence of cardiovascular disease are largely related to the social distribution of cardiovascular disease risk factors, of which hypertension is the single most important.5 UK studies have shown an increased prevalence of hypertension (up to three or four times greater) among black people compared to the rest of the population.6–9 With regard to treatment, there is some evidence that detection rates are better for black compared to white patients.10,11 However, it is claimed that black patients on drug treatment for hypertension have overall poorer blood pressure control.10 While in the US this has been a consistent finding, this has not always been replicated in UK studies.11–13 This may be because these are based on either very small and geographically highly specific populations,10 or conversely, that they rely on national survey data which, despite oversampling, leads to a relatively small and diffuse black and ethnic minority (BEM) sample.12,13
Looking at inequalities in terms of deprivation, there is evidence to show that the Quality and Outcomes Framework (QOF) has led to an incremental reduction in the inequalities gap.14 This is particularly so for blood pressure treatment, where a recent study has shown that differences between practice outcomes in the most and least deprived areas have narrowed to the point of convergence.15 The latter study also found the proportion of black residents in a practice area had the greatest confounding effect. Only one study has, so far, looked specifically at ethnic differences in blood pressure treatment since the QOF was introduced.16 This south west London study found that black patients with hypertension were significantly less likely to achieve QOF blood pressure targets compared to their white counterparts (odds ratio [OR] = 0.86, 95% confidence interval [CI] = 0.74 to 0.99). It is possible that, since then, there has been a reduction in ethnic inequalities in the same way that deprivation inequalities have reduced. This study set out to examine this by looking at ethnic inequalities in blood pressure monitoring and control, using recently collected data from a large sample of practices in Lambeth, south east London.
METHOD
The Lambeth DataNet was used to compare QOF blood pressure outcomes for patients with the following cardiovascular-related diseases: diabetes, CHD, stroke, hypertension, and chronic kidney disease (CKD).
Study design
The dataset comprises electronic patient records from practices in Lambeth. Lambeth has the second highest proportion of ‘black’ or ‘black British’ residents in the UK, at 25.8% (neighbouring Southwark has the highest proportion at 25.9%).17
The database was originally set up to improve both the level and quality of ethnicity coding in GP data, in order to facilitate ethnic monitoring of health inequalities.18 Several strategies were used to improve both the level and quality of ethnicity coding.19
Study sample
To facilitate data extraction, the study sample was restricted to only those practices using the EMIS (Egton Medical Information Systems) LV computer system, comprising just over half (27/53) the GP practices in Lambeth. The study sample covered all patients (192 432) from these practices, and data were extracted from local practice computer systems in March 2009, using MIQUEST software.
How this fits in
High blood pressure has been shown to be more prevalent among black and ethnic minority groups; however, studies looking at drug treatment for hypertension have shown inconsistent results when comparing blood pressure monitoring and control. This study looked at a large sample of primary care patients in Lambeth and found that African–Caribbean patients with hypertension had more frequent blood pressure recording compared to white- British patients. Nevertheless, blood pressure control was significantly worse in African–Caribbean patients.
Outcome measures
Outcomes for blood pressure monitoring and control were primarily based on QOF targets for each chronic disease. Blood pressure monitoring was coded as positive for those with diabetes, CHD, stroke, and CKD, if there was a record of blood pressure measured in the past 15 months and, for hypertension, the past 9 months. Blood pressure control was coded as positive for those with hypertension, CHD, or stroke if their last recorded blood pressure was 150/90 mmHg or less. For patients with diabetes, the target was 145/85 mmHg or less, and for those with CKD 140/85 mmHg or less. The most recent systolic, diastolic, and mean arterial pressures were also examined; the latter was calculated as: [(systolic blood pressure) + (2 × diastolic blood pressure)]/3.20
Predictors
Patient ethnicity codes were mapped on to UK census ethnic categories.17 Initially outcomes were compared for white (white British), black (black or black British) and Asian (Asian or Asian British) patients. It has been argued that more detailed ethnic definitions are justified when exploring differences in blood pressure treatment.9 Therefore, a subgroup analysis was conducted comparing patients in the more detailed ‘other white’ (excluding those coded English, Scottish, Welsh, or Northern Irish), black African and black Caribbean census categories. For brevity, the terms African and Caribbean will be used when referring to the latter ethnic groups, and white when referring to the white British group.
Relative social deprivation was assessed at patient level by mapping patient postcodes to lower super output areas and assigning the Index of Multiple Deprivation (IMD 07) score21 for each patient's immediate neighbourhood. Age, sex, and number of comorbidities (of the five specified chronic diseases) were also adjusted for.
Statistical analysis
The effect of ethnicity on whether patients met QOF blood pressure targets was assessed using logistic regression in Stata (version 10). Recent blood pressure levels were also analysed as a continuous outcome using multiple regression. For each analysis, the standard errors were adjusted to account for the effect of clustering at practice level, using the Huber/White sandwich estimating procedure.
RESULTS
Ethnicity data were obtained for 129 700 (67.3%) patients and, of these, 19 800 had a record of at least one of the five specified chronic disease groups. The main ethnic groups comprised 6543 (33%) classified as white British; 2999 (15.1%) Caribbean; and 2313 (11.7%) African (Table 1). Patients with and without ethnicity data were compared and no sex difference was found, although there was a small age effect, with those whose ethnicity was uncoded being slightly younger (mean age 62.2 years) than those with ethnicity data (mean age 63.3 years), and this difference was statistically significant (P<0.001).
Table 1.
White British n = 6543 | Other white, n = 150 | Asian, n = 1092 | Caribbean, n = 2999 | African, n = 2313 | Total, n = 14 297 | |
---|---|---|---|---|---|---|
Age, years | 67.3 | 61.7 | 61.3 | 63.3 | 54.9 | 63.5 |
Sex, % male | 49.1 | 48.4 | 52.7 | 40.2 | 46.3 | 47.0 |
Comorbidities, n | 1.5 | 1.4 | 1.6 | 1.5 | 1.3 | 1.5 |
Area social deprivation score (IMD 07) | 33.7 | 35.0 | 32.5 | 36.8 | 38.7 | 35.2 |
Table 2 shows how each chronic disease was distributed among the five main ethnic groups in the study sample. While ethnic differences here are broadly in line with what would be expected, it is notable that Caribbean, and not African, patients were over-represented in the hypertension group. However, when the results were adjusted for age and sex, this difference disappeared.
Table 2.
White British, n = 50 396 | Other white, n = 21 874 | Asian, n = 6972 | Caribbean, n = 12 193 | African, n = 15 140 | Total, n = 106 575 | |
---|---|---|---|---|---|---|
Diabetes, % (n) | 3.0 (1508) | 2.1 (459) | 8.0 (556) | 9.9 (1208) | 4.9 (737) | 4.2 (4468) |
Hypertension, % (n) | 10.4 (5217) | 4.7 (1025) | 11.5 (802) | 21.6 (2630) | 12.8 (1939) | 10.9 (11 613) |
Coronary heart disease, % (n) | 2.0 (1030) | 0.8 (175) | 2.9 (202) | 1.5 (186) | 0.4 (67) | 1.6 (1660) |
Stroke, % (n) | 3.0 (643) | 1.8 (104) | 2.8 (73) | 3.7 (231) | 1.8 (99) | 2.8 (1150) |
Chronic kidney disease, % (n) | 2.2 (1097) | 0.6 (141) | 1.9 (131) | 3.2 (386) | 1.0 (152) | 1.8 (1907) |
Any of the above, % (n) | 13.0 (6543) | 6.2 (1350) | 15.7 (1092) | 24.6 (2999) | 15.3 (2313) | 13.4 (14 297) |
To ensure that the practice sample was not subject to selection bias, it was compared with the remaining Lambeth practices on the following key variables: list size; area deprivation and ethnic composition (based on practice postcode); and average age of registered patients. No significant differences were found between the two practice groups.
The analysis of blood pressure monitoring showed little evidence of any ethnic inequality (Table 3). Caribbean patients were more likely to have their blood pressure monitored recently in the diabetes (OR 1.94; 95% CI = 1.12 to 3.35) and hypertension groups (OR 1.32; 95% CI = 1.05 to 1.66). Also, stroke patients in the other white group stood out as being significantly more likely to have their blood pressure monitored (OR 3.76; 95% CI = 1.00 to 14.05). When the results for all chronic diseases patients were pooled, the Caribbean group were, overall, more likely to have their blood pressure monitored (OR 1.32; 95% CI = 1.07 to 1.64), as were patients in the Asian group (OR 1.34; 95% CI = 1.08 to 1.67).
Table 3.
White British | % | Other white, OR (95% CI) | % | Asian, OR (95% CI) | % | Caribbean, OR (95% CI) | % | African, OR (95% CI) | % | Blackb (combined), OR (95% CI) | % | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Diabetes | – | 94.6 | 0.76 (0.52 to 1.11) | 93.1 | 0.85 (0.48 to 1.51) | 93.7 | 1.94 (1.12 to 3.35)c | 97.1 | 0.96 (0.61 to 1.51) | 94.4 | 1.27 (0.88 to 1.83) | 95.8 |
Hypertension | – | 84.2 | 0.89 (0.75 to 1.06) | 82.7 | 1.33 (0.95 to 1.87) | 87.7 | 1.32 (1.05 to 1.66)c | 87.6 | 1.12 (0.86 to 1.46) | 85.7 | 1.22 (0.98 to 1.52) | 86.7 |
Coronary heart disease | – | 91.7 | 1.17 (0.63 to 2.16) | 92.8 | 1.95 (0.78 to 4.85) | 95.5 | 2.31 (0.72 to 7.34) | 96.2 | 1.41 (0.40 to 4.97) | 93.9 | 1.75 (0.83 to 3.72) | 95.4 |
Stroke | – | 89.6 | 3.76 (1.00 to 14.05)a | 97.0 | 2.30 (0.47 to 11.19) | 95.2 | 0.95 (0.41 to 2.21) | 89.1 | 0.71 (0.32 to 1.57) | 86.0 | 0.85 (0.44 to 1.65) | 88.2 |
Chronic kidney disease | – | 92.5 | 0.94 (0.40 to 2.23) | 92.1 | 1.15 (0.36 to 3.64) | 93.4 | 1.68 (0.41 to 6.83) | 95.4 | 0.97 (0.38 to 2.46) | 92.3 | 1.20 (0.55 to 2.62) | 93.8 |
All diseases | – | 85.6 | 0.94 (0.80 to 1.10) | 84.8 | 1.34 (1.08 to 1.67)d | 88.9 | 1.32 (1.07 to 1.64)c | 88.7 | 1.06 (0.85 to 1.33) | 86.3 | 1.18 (0.97 to 1.43) | 87.5 |
OR = odds ratio.
Comparing the odds of patients from a given ethnic group having a positive outcome compared to white British patients. Coefficients are adjusted for age, sex, number of comorbidities, and social deprivation. An odds ratio greater than one indicates improved monitoring and less than one indicates poorer monitoring.
Caribbean and African categories combined.
P<0.05
P<0.01.
In contrast, the successful achievement of QOF blood pressure control targets was less likely, overall, for black patients compared to white patients (OR 0.73; 95% CI = 0.64 to 0.82) (Table 4) and this applied to all but one (stroke) of the chronic disease groups. For example, black patients with CHD were significantly less likely to reach QOF targets for blood pressure control (OR 0.56; 95% CI = 0.39 to 0.81) compared to white patients. A similar magnitude of effect was found for stroke patients, although this did not reach statistical significance, possibly due to the relatively small number of stroke patients in the study sample (Table 2). Not only was blood pressure control shown to be poorer in black patients, but their prevalence of cardiovascular disease-related illnesses was higher, with 19.4% of black patients in the sample having any one of the chronic conditions that were looked at, compared to 13% of the white British group.
Table 4.
White British | % | Other white, OR (95% CI) | % | Asian, OR (95% CI) | % | Caribbean, OR (95% CI) | % | African, OR (95% CI) | % | Blackb (combined), OR (95% CI) | ||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Diabetes | – | 79.4 | 1.12 (0.84 to 1.49) | 81.2 | 0.99 (0.77 to 1.27) | 79.2 | 0.89 (0.72 to 1.08) | 77.3 | 0.63 (0.50 to 0.79)e | 70.7 | 0.78 (0.65 to 0.93)d | 75.6 |
Hypertension | – | 80.6 | 0.97 (0.80 to 1.18) | 80.2 | 1.27 (0.89 to 1.80) | 84.1 | 0.84 (0.72 to 0.98)c | 77.8 | 0.75 (0.63 to 0.89)e | 75.7 | 0.80 (0.70 to 0.91)e | 77.0 |
Coronary heart disease | – | 90.2 | 1.13 (0.73 to 1.73) | 91.2 | 0.79 (0.49 to 1.29) | 87.9 | 0.5 (0.37 to 0.77)e3 | 83.1 | 0.64 (0.28 to 1.46) | 85.5 | 0.56 (0.39 to 0.81)d | 84.5 |
Stroke | – | 87.7 | 0.81 (0.44 to 1.49) | 85.2 | 1.99 (0.86 to 4.60) | 93.4 | 0.70 (0.44 to 1.12) | 83.4 | 0.62 (0.34 to 1.16) | 81.6 | 0.70 (0.45 to 1.07) | 83.5 |
Chronic kidney disease | – | 71.9 | 0.81 (0.58 to 1.14) | 67.5 | 1.53 (0.90 to 2.61) | 79.7 | 0.77 (0.57 to 1.04) | 66.4 | 0.57 (0.36 to 0.90)c | 59.3 | 0.72 (0.55 to 0.95)c | 65.2 |
All diseases | – | 79.2 | 0.99 (0.83 to 1.19) | 79.1 | 1.11 (0.83 to 1.47) | 80.8 | 0.78 (0.66 to 0.91)d | 74.7 | 0.66 (0.57 to 0.76)e | 71.6 | 0.73 (0.64 to 0.82)e | 73.6 |
OR = odds ratio.
Comparing the odds of patients from a given ethnic group having a positive outcome compared to white British patients. Coefficients are adjusted for age, sex, number of comorbidities, and social deprivation. An odds ratio greater than one indicates improved monitoring and less than one indicates poorer monitoring.
Caribbean and African categories combined.
P<0.05.
P<0.01.
P<0.001.
As well as looking at QOF target outcomes, differences in absolute blood pressure levels between ethnic groups were also examined (Table 5). Again this showed black patients achieving poorer blood pressure control, with a mean systolic blood pressure that was 2.96 mmHg (95% CI = 2.17 to 3.75) greater than that of white patients. This also revealed significantly lower blood pressure levels for Asian patients, who had a mean systolic blood pressure that was 1.42 mmHg (95% CI = 2.70 to 0.14) less than that of white patients.
Table 5.
White British | mmHg | Other white, B (95% CI) | mmHg | Asian, B (95% CI) | mmHg | Caribbean, B (95% CI) | mmHg | African, B (95% CI) | mmHg | Blackb (combined), B (95% CI) | mmHg | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Systolic blood pressure | – | 135.2 | −0.06 (−1.56 to 1.45) | 135.1 | −1.42 (−2.70 to −0.14)c | 133.8 | 2.59 (1.57 to 3.61)d | 137.8 | 3.67 (2.53 to 4.80)d | 138.8 | 2.96 (2.17 to 3.75)d | 138.2 |
Diastolic blood pressure | – | 78.4 | −0.09 (−0.77 to 0.59) | 78.3 | −0.34 (−1.27 to 0.60) | 78.0 | 1.89 (1.25 to 2.53)d | 80.3 | 2.06 (1.43 to 2.69)d | 80.4 | 1.94 (1.41 to 2.46)d | 80.3 |
Mean arterial blood pressure | – | 97.3 | −0.07 (−0.93 to 0.80) | 97.2 | −0.68 (−1.34 to −0.03)c | 96.6 | 2.16 (1.42 to 2.90)d | 99.5 | 2.61 (1.93 to 3.30)d | 99.9 | 2.31 (1.74 to 2.88)d | 99.6 |
B = The adjusted mean difference.
Shows the mean difference in blood pressure for patients from a given ethnic group compared to white British patients. Coefficients are adjusted for age, sex, number of comorbidities, and social deprivation.
Caribbean and African categories combined.
P<0.05.
P<0.001.
Looking at the ethnic subgroups, the results show a tendency for African patients to have poorer blood pressure control. For example, the odds of African patients with diabetes meeting QOF targets for blood pressure control were significantly reduced (OR 0.6; 95% CI = 0.50 to 0.79) compared to white patients, whereas for Caribbean patients there was no significant difference. One exception was patients with CHD where, in this case, it was Caribbean patients who showed significantly poorer blood pressure control (OR 0.53; 95% CI = 0.37 to 0.77), while Africans failed to show a significant difference.
This may reflect the higher prevalence of CHD in the Caribbean sample, which was almost twice that of the African sample. When the model was re-run, directly comparing blood pressure control for Africans and Caribbeans, the above differences failed to reach statistical significance. An exception was for patients with diabetes, where African patients showed significantly decreased odds of meeting the QOF blood pressure target compared to Caribbean patients (OR 0.76; 95% CI = 0.59 to 0.97), although this only just reached statistical significance (P = 0.028).
DISCUSSION
Summary of main findings
The study found that overall blood pressure monitoring was at least as good for BEM patients with chronic conditions as for the majority white population. However, black patients were consistently less likely to have their blood pressure adequately controlled.
Therefore, despite evidence that inequality in blood pressure control according to social deprivation has steadily narrowed over the past few years, there has not been a corresponding reduction in ethnic health inequality.
Strengths and limitations of the study
This study benefited from a large sample of patient records covering a range of ethnic groups and chronic conditions. The dataset was particularly suited to this study as Lambeth is an area of contrasting social deprivation with a large BEM population. While this provided enough statistical power to compare the main ethnic groups, it proved to be underpowered for the ethnic subgroup analysis. Also, the data were cross-sectional and, given that Lambeth has a highly mobile population, it is possible that this has affected overall treatment outcomes. For example, some BEM patients may have just begun treatment, after recently moving into the practice area and, therefore, their blood pressure levels may be higher. It was, however, possible to adjust the model to take into account the number of years registered, and this did not make any appreciable difference to the results.
The study was based on data collected as part of the QOF, the limitations of which have been well documented elsewhere.22,23 One possible source of bias in data based on QOF returns is the use of exception reporting to exclude patients.14,15 However, it was possible to overcome this in the present study by accessing data for all patients. As routine administrative data were used, the recorded diagnoses were not independently verified and there might be systematic bias in recording comorbidities. Lifestyle factors are another area where QOF data are relatively limited, and it was not possible to account for differences in exercise, diet, or obesity, all of which may be relevant confounders. It is worth noting that when the effect of smoking was examined, it was found that this made little difference to the results; hence this was excluded from the analysis.
Comparison with existing literature
The encouraging results for blood pressure monitoring for BEM patients are comparable with those of previous studies.8,11 Cappuccio et al found that black people with hypertension were more likely to be detected, although less well managed, than white people.8 It has been argued that blood pressure monitoring rates are relatively good for BEM patients, due to a greater awareness among GPs of ethnic differences in hypertension.10 Another factor may simply be that monitoring can be more easily conducted on an opportunistic basis, while achieving adequate blood pressure control itself demands sustained therapeutic effort and patient engagement, posing a greater clinical management challenge.24
The study results also confirm those of previous studies reporting poorer blood pressure control for black people with chronic conditions.8,16,25 It is notable that those studies that have so far failed to show any ethnic difference were based on smaller samples of BEM patients, because either they relied on national survey data,11,13 or they were concentrated in a small locality.12 For example, Nazroo et al looked at patients treated for hypertension in four waves (1998–2004) of the Health Survey for England, and detected only minimal ethnic differences in blood pressure control.11 Despite being confined to one local authority area, the present study benefited from a larger sample of BEM patients, and therefore had potentially greater power to detect a difference.
It is notable that the results showing a significant ethnic difference remain well within the 95% confidence intervals of those reported in the latter study. A further factor may be that the present study, by concentrating on one large urban area, is well placed to represent the experience of BEM patients, given that the majority of the BEM population is concentrated in a few urban areas in the UK. Despite some effort to represent more concentrated BEM populations, much of the Health Survey for England sample covers BEM participants in areas that are predominantly white.26 It is possible, therefore, that ethnic differences in treatment may be much less distinct in these areas, explaining the overall lack of difference reported by studies using these data.11,13,27 Conversely, the present results are very similar to those reported in a similar study in south west London.16 Using data collected up to the beginning of 2006, the latter study looked at records for GP patients with hypertension soon after QOF was introduced. That the present findings are so similar suggests that there has been little subsequent reduction in ethnic health inequalities.
The results of the present study also suggest that African individuals may have poorer blood pressure control compared to Caribbean people. However, there is very little previous research in this area to compare this with. While the present study looks at those with chronic diseases, only two previous studies have compared blood pressure for African and Caribbean patients overall, and both failed to show any significant difference, although both studies were based on much smaller samples.6,8 There has, though, been some interesting recent research that points to important differences in cerebrovascular risk between these two ethnic groups.28
Implications for future research and clinical practice
Poor blood pressure control has important implications for cardiovascular disease risk and, it has been argued that because hypertension is largely treatable, even small ethnic differences can have major implications for health resources.29 It has been established that lowering blood pressure levels results in a proportional decrease in cardiovascular disease risk, with a reduction of 5 mmHg diastolic blood pressure corresponding to a 34% reduction in the risk of stroke and a 21% reduction in the risk of ischaemic heart disease.30 On this basis, the present findings translate into a substantial additional cardiovascular disease risk for black patients with hypertension. The study was not confined to patients with hypertension but looked also at those with other chronic diseases for which poor blood pressure control increases overall cardiovascular disease risk. Of particular concern are stroke patients, where the mortality risk is much higher in the black population.1 While the present results for stroke patients did not achieve statistical significance they are consistent with the overall pattern of poorer blood pressure control in black patients. The study also looked at different ethnic subgroups, and further study is now needed to see if the results are replicated in other African–Caribbean communities.
While this study was able to show some clear ethnic differences in achievement of blood pressure targets, the mechanism behind this can only be speculated at this stage. It is possible that medication adherence, differentiated by ethnic group, may partly explain these differences, as some US studies have demonstrated,31,32 although further research is needed to establish this. Another question is whether black patients are being prescribed lower volumes of drugs to treat hypertension. More fundamentally, poorer blood pressure control in black patients with hypertension and other chronic diseases related to cardiovascular disease, may reflect higher population norms for mean blood pressure values in the black population.7 In consequence, this could mean that greater blood pressure reductions are required for this group to achieve fixed blood pressure targets. Another factor may be whether or not GPs adhere to ethnic-specific treatment guidelines for blood pressure management,33 and further work is needed to explore the different classes of medication prescribed and how these might contribute to ethnic differences in blood pressure outcomes. The authors are, therefore, currently working on a follow-on study looking specifically at the relationship between blood pressure control and the class of blood pressure drugs prescribed.
Acknowledgments
We would like to acknowledge the contribution of the Lambeth patients and practices who allowed us access to their data.
Funding body
The study was supported by a grant from the Guy's and St. Thomas' Charity.
Ethical approval
Ethical approval was given by the South East Research Ethics Committee – 07MRE01/26
Competing interests
The authors have stated that there are none
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