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. 1987 Nov 25;15(22):9215–9225. doi: 10.1093/nar/15.22.9215

Unusual features of CpG-rich (HTF) islands in the human alpha globin complex: association with non-functional pseudogenes and presence within the 3' portion of the zeta gene.

N Fischel-Ghodsian 1, R D Nicholls 1, D R Higgs 1
PMCID: PMC306463  PMID: 2825132

Abstract

We have characterised a cluster of CpG rich (HTF) islands in the alpha-globin complex and report here two unusual features: The human embryonic zeta 2-globin gene is associated with an HTF island within its 3' portion rather than at the 5' end. Furthermore at least two non-functional pseudogenes within the cluster (psi zeta 1 and psi alpha 2) are associated with CpG rich islands.

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Selected References

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