Salmonella maintains the integrity of its intracellular vacuole through the action of SifA. Beuzón Carmen R., Méresse Stéphane, Unsworth Kate E., Ruíz-Albert Javier, Garvis Steve, Waterman Scott R., Ryder Timothy A., Boucrot Emmanuel, Holden David W. The EMBO Journal. 2000;19:3235–3249. doi: 10.1093/emboj/19.13.3235.
The publishers apologize for the error printed in the footnotes of Table I. Table I is shown correctly below.
Table I. Competitive Index analysis of S.typhimurium mutants.
| Mixed infectiona | C.I.b |
|---|---|
| Controls | |
| wt versus ssaV– | 0.006 |
| wt versus purD– | 0.0005 |
| ssaV– versus ssaV–, purD– | 0.0038d |
| purD– versus ssaV–, purD– | 0.019d |
| wt versus ssaV–, purD– | 0.00006 |
| wt versus sseB– | 0.016 |
| ssaV– versus ssaV–, sseB– | 1.2c |
| sseB– versus ssaV–, sseB– | 0.82c |
| wt versus ssaV–, sseB– | 0.014 |
| ompR/envZ | |
| wt versus ompR– | 0.008 |
| ssaV– versus ssaV–, ompR– | 0.823c |
| ompR– versus ssaV–, ompR– | 0.21c |
| wt versus ssaV–, ompR– | 0.010 |
| sifA | |
| wt versus sifA– | 0.012 |
| sifA– psifA versus sifA– | 0.074d |
| ssaV– versus ssaV–, sifA– | 1.34c |
| sifA– versus ssaV–, sifA– | 1.17c |
| wt versus ssaV–, sifA– | 0.0019 |
aStrains used in the mixed infection experiments are referred to by the relevant genotype and are described in Table II. The ssaV– strain used was marked with either Km or Cm resistance cassettes to distinguish it from the competing strain.
bThe C.I. was calculated as the output ratio of mutant or double mutant to wild-type or single mutant bacteria, divided by the input ratio. The C.I.s shown are the means of three independent infections of mice. Mice were inoculated i.p. with a mixture of two strains comprising ∼5 × 104 c.f.u. of each strain. Mouse spleens were harvested after 48 h for enumeration of bacterial c.f.u. The different strains used were differentiated on the basis of antibiotic sensitivity. The C.I.s of double mutant versus single mutant strains were analysed by Student’s t-test.
cNot significantly different from 1.0 (p <0.05).
dNot significantly different from the C.I. of the corresponding single mutant strain versus wild-type strain.
