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Immunohistochemistry of hypoxia-inducible factor-1α (HIF-1α) (A, C) and human growth and transformation-dependent protein (HGTD-P) (B, D) in identical tumour samples. A, B, Tumour cells strongly expressed both HIF-1 and HGTD-P. C, D, The tumour expressed neither HIF-1α nor HGTD-P.
