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Neutrophil adhesion to HUVEC in the presence of integrin-specific blocking monoclonal antibodies. Neutrophils (2x106 cells/mL) from controls (A, n=6) or from SCD individuals (B, n=8) were allowed to adhere to HUVEC for 30 min at 37°C, 5% CO2, in the presence or absence of integrin-blocking monoclonal antibody, as indicated. *P<0.05; **P<0.01; ***P<0.001, compared to basal adhesion; Friedman’s test, followed by Dunn’s multiple comparison between selected groups and basal adhesion.
