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. 2010 Dec 20;96(4):526–533. doi: 10.3324/haematol.2010.032912

Figure 6.

Figure 6.

Effect of simvastatin on spontaneous and IL8-stimulated neutrophil chemotaxis. Spontaneous chemotaxis (Spont) and IL-8 (100 ng/mL)-stimulated chemotaxis of neutrophils from control (n=6) and SCD individuals (n=6) was measured following the pre-incubation (or not) of neutrophils with simvastatin (SIM) (1 μM). ***P<0.001, compared with spontaneous chemotaxis; #P<0.05 compared with IL-8-stimulated control neutrophil chemotaxis; +P<0.05, compared with IL-8-stimulated SCD neutrophil chemotaxis; Friedman’s test, followed by Dunn’s multiple comparison.