Table 4.1.
Synthesis of α-phenoxy-β-aryl-β-lactams.
| Entry | R | dr | ee (%) | Yield (%) |
|---|---|---|---|---|
| 1 | Ph | 25:1 | 94 | 83 |
| 2 | p-F-Ph | 19:1 | 97 | 47 |
| 3 | p-Cl-Ph | 28:1 | 97 | 57 |
| 4 | p-CN-Ph | 12:1 | 94 | 52 |
| 5 | p-NO2-Ph | 16:1 | 94 | 55 |
| 6 | p-Tol | 19:1 | 95 | 69 |
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