Table 2.
Frequencies of CCR2-CCR5 polymorphisms among HIV-1 serodiscordant couples, index partners, and HIV-1 exposed seronegative partners
| HESNa partners | |||||
|---|---|---|---|---|---|
| All (N = 1134) | Index partners (N = 567) | All (N = 567) | Seroconverters (N = 240) | Uninfected (N = 327) | |
| Haplotype | N (%) | N (%) | N (%) | N (%) | N (%) |
| HHA | 601 (26.5) | 305 (26.9) | 296 (26.1) | 133 (27.7) | 163 (24.9) |
| HHB | 44 (1.9) | 25 (2.2) | 19 (1.7) | 8 (1.7) | 11 (1.7) |
| HHC | 178 (7.9) | 69 (6.1) | 109 (9.6) | 42 (8.8) | 67 (10.2) |
| HHD | 370 (16.3 | 190 (16.8) | 180 (15.9) | 75 (15.6) | 105 (16.1) |
| HHE | 310 (13.7) | 138 (12.2) | 172 (15.2) | 61 (12.7) | 111 (17.0) |
| HHF*1 | 128 (5.6) | 76 (6.7) | 52 (4.6) | 24 (5.0) | 28 (4.3) |
| HHF*2 | 480 (21.2) | 259 (22.8) | 221 (19.5) | 99 (20.6) | 122 (18.7) |
| HHG*1 | 157 (6.9) | 72 (6.4) | 85 (7.5) | 38 (7.9) | 47 (7.2) |
| HWE:Pb | 0.0001 | 0.0001 | 0.267 | 0.024 | 0.160 |
a HESN = HIV-1 exposed seronegative
b P values for tests of Hardy-Weinberg equilibrium in each of the patient groups.