MEDICAL SCIENCES, CHEMISTRY Correction for “Multistage nanoparticle delivery system for deep penetration into tumor tissue,” by Cliff Wong, Triantafyllos Stylianopoulos, Jian Cui, John Martin, Vikash P. Chauhan, Wen Jiang, Zoran Popović, Rakesh K. Jain, Moungi G. Bawendi, and Dai Fukumura, which appeared in issue 6, February 8, 2011 of Proc Natl Acad Sci USA (108:2426–2431; first published January 18, 2011; 10.1073/pnas.1018382108).
The authors note that Fig. 2 and its corresponding legend appeared incorrectly. This error does not affect the conclusions of the article. The corrected figure and its corrected legend appear below.
Fig. 2.
QDGelNP physical and in vitro characterization. (A) Epifluorescence image of QDGelNPs on a silicon substrate at 100× magnification. (Scale bar: 5 μm.) (B) DLS distribution of QDGelNP on day 1 and day 48 after synthesis and storage at 4 °C. (C) SEM image of QDGelNPs at 15,000× magnification. (Scale bar: 1 μm.) (C Inset) SEM image of individual QDGelNP at 35,000× magnification. (Scale bar: 100 nm.) (D) Histogram of QDGelNPs’ size distribution from image analysis of SEM image. (E and F) Kinetics of MMP-2–induced QD release from QDGelNPs. (E) QD-release curve from incubation of 0.1 mg of QDGelNPs with 230 ng (0.16 μM) of MMP-2. (F) QD release from incubation of 0.1 mg of QDGelNPs for 12 h with varying amounts of MMP-2. (G and H) FCS cross-correlograms of QDGelNPs before (G) and after (H) incubation with MMP-2.