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. 1994 Jan 11;22(1):66–71. doi: 10.1093/nar/22.1.66

A novel nuclear receptor superfamily member in Xenopus that associates with RXR, and shares extensive sequence similarity to the mammalian vitamin D3 receptor.

D P Smith 1, C S Mason 1, E A Jones 1, R W Old 1
PMCID: PMC307747  PMID: 8127656

Abstract

We report the isolation of xONR1, a novel member of the nuclear receptor superfamily from Xenopus laevis. xONR1 shares a high degree of amino acid sequence identity with the mammalian receptor for 1 alpha, 25-dihydroxy vitamin D3, particularly within the DNA-binding domain, although it does not bind this ligand. xONR1 DNA binding is stimulated by association with retinoid X receptor gamma (RXR gamma).

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Selected References

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