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. 1994 Jul 11;22(13):2476–2478. doi: 10.1093/nar/22.13.2476

Prediction of an rRNA methyltransferase domain in human tumor-specific nucleolar protein P120.

E V Koonin 1
PMCID: PMC308198  PMID: 8041608

Abstract

Using computer methods for identification of amino acid motifs in sequence databases and multiple alignment, it is shown that human proliferation-associated nucleolar protein P120 contains a putative methyltransferase domain that is conserved in a group of bacterial proteins. It is hypothesized that P120 and the related prokaryotic proteins are rRNA methylases required for division of all types of cells.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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