Abstract
In 1991 the Genome Data Base at Johns Hopkins University School of Medicine was selected as the central repository for mapping data from the Human Genome Project, and was funded by NIH and DOE under a three year award. GDB has now finished 28 months of Federally funded operation. During this period a great deal of progress and many internal changes have taken place. In addition, many changes have also occurred in the external environment, and GDB has adapted its strategies to play an appropriate role in those changes as well. Recognizing the central role of mapping information in the genome project, it is important that GDB respond aggressively to the increasing demands of genomic researchers, as well as formulate a program of response to a number of long standing, but still unmet, needs of that community. It is even more important that GDB provide leadership in the genome informatics enterprise. Three themes described here are dominant in our future plans and represent the essence of the major changes made in the past year. They include: enhanced data acquisition, better map representation, and full integration into the collection of genomic databases.
Full text
PDF







Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Cuticchia A. J., Fasman K. H., Kingsbury D. T., Robbins R. J., Pearson P. L. The GDB human genome data base anno 1993. Nucleic Acids Res. 1993 Jul 1;21(13):3003–3006. doi: 10.1093/nar/21.13.3003. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Pearson P. L., Matheson N. W., Flescher D. C., Robbins R. J. The GDB Human Genome Data Base Anno 1992. Nucleic Acids Res. 1992 May 11;20 (Suppl):2201–2206. doi: 10.1093/nar/20.suppl.2201. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Woychik R. P., Wassom J. S., Kingsbury D., Jacobson D. A. TBASE: a computerized database for transgenic animals and targeted mutations. Nature. 1993 May 27;363(6427):375–376. doi: 10.1038/363375a0. [DOI] [PubMed] [Google Scholar]