Skip to main content
. 2011 Apr 12;97(11):923–930. doi: 10.1136/hrt.2010.216309

Table 3.

Relative change in serum LDL-cholesterol (mmol/l) between the baseline (1991–3) and follow-up (2003–4) screening as a function of the use of lipid-lowering drugs, healthy diet and physical activity (N=4469)

n Mean relative change in LDL-cholesterol (mmol/l) and p value for difference
Model 1* Model 2 Model 3
Start of lipid-lowering drugs
 None 3954 0 Reference 0 Reference 0 Reference
 Baseline 34 −1.09 <0.001 −1.09 <0.001 −1.14 <0.001
 During follow-up 481 −1.81 <0.001 −1.77 <0.001 −1.77 <0.001
Change in AHEI score
 Increase (≥1 SD) 717 −0.14 <0.001 −0.14 <0.001 −0.07 0.03
 Stable (−1≤ SD <1) 3071 0 Reference 0 Reference 0 Reference
 Decrease (<−1 SD) 681 0.10 0.02 0.10 0.02 0.12 <0.001
Change in physical activity
 Increase (≥1 SD) 601 −0.11 0.007 −0.10 0.02 −0.10 0.005
 Stable (−1≤ SD <1) 3312 0 Reference 0 Reference 0 Reference
 Decrease (<−1 SD) 556 0.09 0.04 0.09 0.03 0.10 0.004
*

Model 1: Adjusted for sex, age at baseline, ethnicity and duration of follow-up.

Model 2: As model 1 and additionally adjusted for education level, BMI at baseline and long-standing illness at baseline.

Model 3: As model 2 with predictors mutually adjusted.

AHEI, alternate healthy eating index; BMI, body mass index; LDL, low-density lipoprotein.