Table 2.
CpG positions | Transcription factors binding within 4 bases | Effects of BaP on methylation |
103 | No sites | ↔ |
137 | SP-1 | ↓ |
205 | SP-1, AP-1, ERα, C/EBPβ | ↓ |
252 | AP1, CREB | ↓ |
351 | c-myc, LBP-1 | ↓ |
418 | Sp-1 | ↓ |
Transcription factor binding sites located at (or in proximity to) CpG sites analyzed. The right column shows the effects of BaP treatment on methylation at that CpG position.