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. Author manuscript; available in PMC: 2012 Jun 1.
Published in final edited form as: Bone. 2011 Apr 5;48(6):1305–1312. doi: 10.1016/j.bone.2011.03.765

Figure 1. Characterization of Differences between Peripheral Weight-Bearing Bone of Subjects with Thalassemia Compared to Healthy Controls.

Figure 1

Footnote: This figure summarizes the findings from the pQCT variables in the tibia of patients with thalassemia compared to healthy controls. The findings are significant after adjustment for age, gender, Tanner stage, growth (tibial length Z-score) and/or tibial muscle mass. Of note, decreased periosteal circumference and reduced cortical thickness may lead to a mechanically weaker bone. However, in this study after controlling for tibial length and muscle mass, there was no significant differences in the strength parameter observed (Section Modulus Z-score).